A 10-panel expands the standard 5-panel to include prescription drug classes: benzodiazepines (Xanax, Valium), barbiturates, methadone, propoxyphene, and methaqualone. Employers in safety-sensitive industries and positions involving medication access (healthcare, pharmacy) typically choose the 10-panel. We provide both, $50 and $70 respectively, with chain-of-custody documentation and MRO review for non-negative results.